KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IQGAP1
All Species:
8.79
Human Site:
T474
Identified Species:
32.22
UniProt:
P46940
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46940
NP_003861.1
1657
189252
T474
L
E
S
G
D
V
N
T
V
W
K
Q
L
S
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536199
1657
189148
T474
L
E
S
G
D
M
N
T
V
W
K
Q
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKF1
1657
188738
T474
L
E
S
G
D
M
T
T
V
W
K
Q
L
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509899
540
60910
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082590
1618
184741
E461
N
L
Q
R
Y
I
D
E
L
I
R
M
K
Q
Q
Zebra Danio
Brachydanio rerio
NP_001121812
1680
191619
A484
L
D
T
K
D
S
V
A
V
I
E
Q
L
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203784
771
87814
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97
N.A.
95.9
N.A.
N.A.
28.2
N.A.
80.5
62
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
N.A.
N.A.
98.5
N.A.
98
N.A.
N.A.
30.8
N.A.
89.1
77.9
N.A.
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
86.6
N.A.
N.A.
0
N.A.
0
40
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
N.A.
N.A.
0
N.A.
26.6
60
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
58
0
15
0
0
0
0
0
0
0
15
% D
% Glu:
0
43
0
0
0
0
0
15
0
0
15
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
43
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
0
0
0
29
0
0
0
0
0
% I
% Lys:
0
0
0
15
0
0
0
0
0
0
43
0
15
0
0
% K
% Leu:
58
15
0
0
0
0
0
0
15
0
0
0
58
0
0
% L
% Met:
0
0
0
0
0
29
0
0
0
0
0
15
0
0
0
% M
% Asn:
15
0
0
0
0
0
29
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
15
0
0
0
0
0
0
0
0
58
0
15
15
% Q
% Arg:
0
0
0
15
0
0
0
0
0
0
15
0
0
0
0
% R
% Ser:
0
0
43
0
0
15
0
0
0
0
0
0
0
58
43
% S
% Thr:
0
0
15
0
0
0
15
43
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
15
15
0
58
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
43
0
0
0
0
0
% W
% Tyr:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _